Mac Live is a Cocoa front end to xbox.com. It can provide Growl alerts when selected friends come online or when certain games are being played by your friends.
Update
Install the Safari 3 beta from Apple and all Mac Live memory leaks automagically disappear!
Progress
New in V6: Accept/Reject friend requests actually works now :)
In response to the recent interest in Mac Live I have been working on improving it. Aside from documentation, I have developed all of the features that I had hoped to be able to provide for my first official release. At this point I'm looking at doing an official release soon (how soon depends on the bug reports I receive from users). Below is the current feature list:
View friends, games, and messages
Notifications via growl when selected friends or selected games come online
Notifications via growl when messages or friend requests are received
Send friend requests (both via the services menu in any application and within Mac Live itself)
Send text messages to friends
Delete messages
Accept or Reject friend requests